Ashwagandha: What the Research Shows

Ashwagandha is the most-studied adaptogen, with randomized trials reporting reduced stress and improved sleep. Here’s the evidence, the doses used, and the caveats.

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Ashwagandha (Withania somnifera) is an Ayurvedic herb classed as an “adaptogen” — a plant said to help the body cope with stress. It is the most-studied adaptogen, and the trial evidence is moderate and encouraging.

Stress and anxiety

A systematic review and meta-analysis concluded that ashwagandha supplementation reduced stress and anxiety versus placebo. An earlier randomized, double-blind, placebo-controlled trial reported lower perceived stress and serum cortisol with a standardized root extract.

Sleep

A randomized, placebo-controlled trial found ashwagandha root extract improved sleep parameters and anxiety. Effects build over weeks of daily use.

The caveats

Trials use standardized root extracts at specific doses, so results don’t automatically transfer to any product. Ashwagandha is generally well tolerated short-term, but it isn’t recommended in pregnancy and can interact with thyroid, sedative, or immune medications — check with a clinician if that’s you.

Frequently asked questions

Does ashwagandha reduce stress?

A systematic review and meta-analysis found ashwagandha reduced stress and anxiety versus placebo, and a randomized trial reported lower perceived stress and cortisol with a standardized root extract.

Does ashwagandha help sleep?

A randomized, placebo-controlled trial found ashwagandha root extract improved sleep and anxiety over several weeks of daily use.

Who should avoid ashwagandha?

It is not recommended in pregnancy and may interact with thyroid, sedative, or immune-affecting medications. Check with a clinician if any apply.

Sources

  1. Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysis · Explore (New York, N.Y.), 2024
  2. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults · Indian Journal of Psychological Medicine, 2012
  3. Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study · Cureus, 2019